CircSeqAlignTk: An R package for end-to-end analysis of RNA-seq data for circular genomes

نویسندگان

چکیده

RNA sequencing (RNA-seq) technology has now become one of the standard tools for studying biological mechanisms at transcriptome level. Advances in RNA-seq have led to emergence a large number publicly available data analysis. Most them target linear genome sequences although it is necessary study organisms with circular sequences. For example, by infection viroids which comprise 246–401 nucleotides RNAs and plants, tremendous economic agricultural damage may be prevented. Unfortunately, using construct workflows analysis difficult, especially non-bioinformaticians. To overcome this limitation, we present CircSeqAlignTk, an easy-to-use richly documented R package. CircSeqAlignTk performs end-to-end analysis, from alignment visualization sequences, through series functions. Additionally, implements function generate synthetic that mimics real obtained experiments. not only provides interface novice users but also allows developers evaluate performance new workflows.

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ژورنال

عنوان ژورنال: F1000Research

سال: 2022

ISSN: ['2046-1402']

DOI: https://doi.org/10.12688/f1000research.127348.1